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Bioimplants with extra-cellular vesicles from stem cells can improve cardiac function after an acute myocardial heart attack

Researchers from the ICREC Group (Cardiac Insufficiency and Regeneration in cardiovascular diseases) at the Germans Trias i Pujol Research Institute (IGTP) continue to work on therapeutic technologies to repair cardiac tissue after a heart attack in collaboration with the IVECAT group (IGTP). In an article published in Theranostics, they present a study of extracellular vesicles […]

Prácticas y Ceremonia de clausura del Curso Avanzado en EVs

Overall Survival and Biomarker Analysis of Neoadjuvant Nivolumab Plus Chemotherapy in Operable Stage IIIA Non–Small-Cell Lung Cancer

Te group of Dr Atocha Romero has just published the terrific results of the NADIM phase II trial, showing that ctDNA levels were significantly associated with OS and outperformed radiologic assessments in the prediction of survival. The manuscript is available at https://ascopubs.org/doi/full/10.1200/JCO.21.02660#.YoK7H6Useqs.twitter

1st – Geivex MOVE Fellowships Awardees

Characterization of plasma circulating small extracellular vesicles in patients with metastatic solid tumors and newly diagnosed brain metastasis

A new piece of work from Dr Peinado´s group in which the medical oncologist Alberto Carretero, co-supervised with Guillermo De Velasco Oria de Rueda and Marta Herguetas characterize in depth circulating EVs from patients with brain metastasis. The manuscript is available at

Tetraspanins interweave EV secretion, endosomal network dynamics and cellular metabolism

As part of a Special Issue on EVs on the European J Cell Biology, Víctor Toribio and María Yáñez-Mó discuss how tetraspanins regulate endosomal dynamics and thus impact on EV secretion and cellular metabolism revieweing intriguing new data on this interesting superfamily of proteins. The manuscript is freely available to the scientific community at

Commonly used methods for extracellular vesicles’ enrichment: Implications in downstream analyses and use

As part of the Special Issue on EVs at the European Journal of Cell Biology, Marta Clos-San Salvador and Marta Monguió-Tortajada from Dr Borrás´s group (REMAR-IVECAT Research Group (Kidney Related Pathologies Research Group – Innovation in Vesicles and Cells for Application in Therapy) at IGTP (Germans Trias i Pujol Health Sciences Research Institute)) nicely update […]

Commonly used methods for extracellular vesicles’ enrichment: Implications in downstream analyses and use

As part of a Special Issue on EVs on the European J Cell Biology, a nice update from Dr Borrás group on EV enrichment techniques that will help in decision making for downstream analyses. The manuscript is freely available to the scientific community at

The Contribution of Extracellular Vesicles From Senescent Endothelial and Vascular Smooth Muscle Cells to Vascular Calcification

A mini-review article from GEIVEX members Dr Consuelo Borrás and Dr Matilde Alique. Vascular calcification is an irreversible pathological process associated with a loss of vascular wall function. This process occurs as a result of aging and age-related diseases, such as cardiovascular and chronic kidney diseases, and leads to comorbidities. During these age-related diseases, the […]