June 14, 2021

Hector Peinado recibe una Beca Leonardo de la fBBVA

Enhorabuena a Hector por el apoyo de la FUndación BBVA a su proyecto para el desarrollo de nuevos ensayos de biopsia liquida en melanoma.  Héctor Peinado Selgas, jefe de grupo en el Centro Nacional de Investigaciones Oncológicas (CNIO). “Análisis de la mutación BRAF en exomas circulantes de pacientes de melanoma”. Subárea: Investigación traslacional. https://www.redleonardo.es/noticias/adjudicadas-58-becas-leonardo-a-investigadores-y-creadores-culturales-en-9-areas-de-la-ciencia-y-la-cultura/

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May 31, 2021

Mª Jesús Vicent Docón, recibe el premio Concepción Aleixandre de Picanya a la Mujer Científica Valenciana

La investigadora Mª Jesús Vicent Docón, investigadora en polímeros terapéuticos ha sido premiada en la categoría de Comunitat Valenciana. El Ayuntamiento de Picanya entregó los galardones el viernes 28 de Mayo , coincidiendo con el Día Internacional de Acción por la Salud de las Mujeres. Esta tercera edición de los galardones se ha enfocado a […]

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May 12, 2021

CD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells

A TeNTaCLES collaboration between Yáñez-Mó and Peinado´s groups. Discover how: Tetraspanins are much more than EV markers Plasma membrane is an important source for EV cargo EV biogenesis impacts on mitochondrial quality control Biomedical potential of tetraspanin-targeted blocking peptides in tumor growth All the details at  http://doi.org/10.1002/jev2.12082

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April 16, 2021

Targeting Alzheimer’s disease with multimodal polypeptide-based nanoconjugates

Alzheimer’s disease (AD), the most prevalent form of dementia, remains incurable mainly due to our failings in the search for effective pharmacological strategies. Here, we describe the development of targeted multimodal polypeptide-based nanoconjugates as potential AD treatments. Treatment with polypeptide nanoconjugates bearing propargylamine moieties and bisdemethoxycurcumin or genistein afforded neuroprotection and displayed neurotrophic effects, as […]

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March 24, 2021

Biomaterial scaffolds containing extracellular vesicles from stem cells to control and promote heart muscle repair after heart attack

Local administration of porcine immunomodulatory, chemotactic and angiogenic extracellular vesicles using engineered cardiac scaffolds for myocardial infarction A collaboration between the iCREC and the IVECAT-REMAR groups from the Institute Germans Trias i Pujol (IGTP) has brought some new light into the therapeutic potential of MSC derived EVs. Check all the details in the link below. […]

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January 22, 2021

DNA-Loaded Extracellular Vesicles in Liquid Biopsy: Tiny Players With Big Potential?

Extracellular vesicles, tiny players with big potential ?, some ideas published by Susana Garcia Silva, Miguel Gallardo and Hector Peinado https://www.frontiersin.org/articles/10.3389/fcell.2020.622579/full?&utm_source=Email_to_authors_&utm_medium=Email&utm_content=T1_11.5e1_author&utm_campaign=Email_publication&field&journalName=Frontiers_in_Cell_and_Developmental_Biology&id=622579%E2%80%AC&fbclid=IwAR3ZlWgLIcdyjrsOEPMDZjQXiCrfBh8wtM0ptCRayh6D4Vm7ivjEtIYbBuc

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January 20, 2021

Dr Marcilla elected as corresponding academic of the Spanish Royal Academy of Pharmacy

We are happy to announce that Dr Marcilla has been recently elected as corresponding academic at the Spanish Royal Academy of Pharmacy. Our TeNTaCLES network now counts with two academics (Dr Sánchez-Madrid and Dr Marcilla)! We will be looking forward to his position taking act to celebrate it!. Congrats!

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January 18, 2021

HUMAN OBESE WHITE ADIPOSE TISSUE SHEDS DEPOT-SPECIFIC EXTRACELLULAR VESICLES AND REVEALS CANDIDATE BIOMARKERS FOR MONITORING OBESITY AND ITS COMORBIDITIES

The group of Dr Pardo have have published a ground-breaking study of EVs on Obesity and its comorbidities. They isolated and characterized extracellular vesicles (EVs) shed by whole human obese visceral (VAT) and subcutaneous (SAT) adipose tissues to perform the first proteome reference map and comparative analysis. Further validation shows that obese AT release EVs […]

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