A TeNTaCLES collaboration between Yáñez-Mó and Peinado´s groups. Discover how: Tetraspanins are much more than EV markers Plasma membrane is an important source for EV cargo EV biogenesis impacts on mitochondrial quality control Biomedical potential of tetraspanin-targeted blocking peptides in tumor growth All the details at http://doi.org/10.1002/jev2.12082
Read MoreLa investigadora Mª Jesús Vicent Docón, investigadora en polímeros terapéuticos ha sido premiada en la categoría de Comunitat Valenciana. El Ayuntamiento de Picanya entregó los galardones el viernes 28 de Mayo , coincidiendo con el Día Internacional de Acción por la Salud de las Mujeres. Esta tercera edición de los galardones se ha enfocado a […]
Read MoreA TeNTaCLES collaboration between Yáñez-Mó and Peinado´s groups. Discover how: Tetraspanins are much more than EV markers Plasma membrane is an important source for EV cargo EV biogenesis impacts on mitochondrial quality control Biomedical potential of tetraspanin-targeted blocking peptides in tumor growth All the details at http://doi.org/10.1002/jev2.12082
Read MoreAlzheimer’s disease (AD), the most prevalent form of dementia, remains incurable mainly due to our failings in the search for effective pharmacological strategies. Here, we describe the development of targeted multimodal polypeptide-based nanoconjugates as potential AD treatments. Treatment with polypeptide nanoconjugates bearing propargylamine moieties and bisdemethoxycurcumin or genistein afforded neuroprotection and displayed neurotrophic effects, as […]
Read MoreDr Valés-Gómez chaired the discussion on different aspects of biomarker discovery based on the detection of EV-associated nucleic acids. Both Dr Otaegui, Dr Peinado and Dr Valés-Gómez presented their results focused on circular RNAs, DNA or mRNA detection, respectively. A lively discussion about methodologies used, limitations and results-driven solutions was held and some ideas and […]
Read MoreLola Fernandez-Messina and Elena Castellano took the lead in organizing the TeNTaCLES Journal Club, which is expected to include all researchers (predoc, postdoc and PIs) of the groups in the network to discuss relevant aspects of EV research. The first Seminar took place on February 22nd and dealt with EVs in cancer and metastasis, with […]
Read MoreDr López-Guerrero summarized the concept of SPREC codes and the data from previous reports analysing the experimental evidence in the literature that supports the effect of preanalytical conditions in which biological samples are obtained in the outcome of EV isolation and characterization. SPREC codes are meant to standardize samples among different laboratories and biobanks. There […]
Read More
